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Brand Names: Sofradex
Generic Name:
Dexamethasone, Framycetin sulphate, Gramicidin
Manufacturer: Sanofi Aventis

How does it work?
Dexamethasone belongs to a group of medicines, known as corticosteroids, used for reducing inflammation. Inflammation occurs as a result of allergy or irritation and is caused by the release of substances that are important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful. Corticosteroids work by acting within cells to decrease the release of these substances in a particular area, thereby reducing swelling, redness and itch.

Framycetin sulphate belongs to a group of antibiotics called aminoglycosides. These antibiotics have the ability to destroy a wide variety of bacteria. Framycetin binds to components in the bacterial cell, which results in the production of abnormal proteins. These proteins are normally necessary for the bacteria's survival, therefore the production of abnormal proteins is ultimately fatal to the bacteria.

Gramicidin is also an antibacterial medicine. The combination of these two antibiotics provides treatment against a wide variety of bacteria that may infect inflamed eye or ear conditions.

What is it used for?
Inflammation and infection of the outer part of the ear canal (otitis externa)
Inflammation of the eye when prevention of bacterial infection is also required
Inflammation of the eyelids (blepharitis) - ointment only

It is recommended that you receive regular eye examinations while you taking this medicine, as it can sometimes cause eye problems. Consult your doctor if you experience any disturbances in your vision while taking this medicine.
Consult your doctor if after seven days of treatment with this medicine there is little or no improvement in your symptoms.
This medicine may cause your vision to blur temporarily after you have applied it into your eye. Do not drive or operate machinery until this has worn off.
Intensive or prolonged application of corticosteroids to the eye may lead to an increase in the pressure inside the eye, glaucoma, damage to the optic nerve or the formation of cataracts.
This medicine is not to be taken by mouth.
Each container of this medicine should discarded four weeks after the first opening. You may find it helpful to write the date of opening on the pack. Dispose of carefully, preferably by returning to your pharmacy.
This medicine should not be used to treat a red eye not diagnosed by a doctor, as inappropriate use can cause blindness.

Use with caution in
Prolonged use

Not to be used in
Fungal or viral infections of the eyes or ears.
Tuberculosis infection affecting the eye.
Eye conditions that are producing pus.
Inflammation of the front of the eye (cornea) or the membrane lining the eye (conjunctiva) due to the herpes simplex virus (herpetic keratitis).
Ear conditions in people with a perforated eardrum.

This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

News Update

February 26, 2018:

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