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Brand Names: Benozyt, Zithromax, Zithromac, Vinzam, Zmax, Aztrin, Zitrocin, Azibiot, Azifine, AziCip, Azi Sandoz
Generic Name: Azithromycin
Binozyt, Azithromycin 250 mg - capsules
1 capsule contains:
Azithromycin dehydrate, corresponding to 250 mg of Azithromycin
Capsule shell: hard gelatin
Other Ingredients: lactose (anhydrous), maize
starch, magnesium stearate, sodium lauryl
Binozyt 250 mg capsules:
single pack of 6 capsules
Pharmaceutical and therapeutic category and mode of action
Binozyt is active against certain bacteria (it is an antibiotic). After you take the medicine, the active ingredient in Binozyt - azithromycin - passes into the bloodstream from the digestive tract and is carried to the diseased tissue, where it starts acting against the bacteria. Because azithromycin remains at the site of infection for longer than other antibiotics, the healing action continues for several days after taking the medicine.
Marketing authorization holder
Sandoz GmbH, Kundl - Austria
Binozyt is suitable for treating the following conditions which are caused by organisms sensitive to azithromycin:
• of the upper and lower respiratory tract, for example infections of the ear, nose and throat, bronchitis, and pneumonia
• of the skin and soft tissues
• of the urinary tract and genitals
If you have already used Binozyt or similar medicines, for example erythromycin, and you had an allergic reaction. Please inform your doctor accordingly.
Pregnancy and breastfeeding
Do not use Binozyt if you are pregnant or breastfeeding!
Precautions for use and special warnings
- if you suffer from impaired liver function, kidney disease or serious gastrointestinal problems with vomiting and diarrhoea
- if you have ever had serious allergies or asthma
- If you are pregnant
Use of Binozyt is not advised in the case of serious liver disease. If side effects occur, for example severe and persistent diarrhoea, please contact your doctor immediately.
Keep out of the reach of children!
Interactions with other medicines
Please tell your doctor if you are taking other medicines along with Binozyt or if you have taken any other medicines recently. For example, adverse reactions could occur if ergot alkaloids (e.g. ergotamin) are used at the same time as Binozyt. Warfarin, cyclosporin, digoxin and terfenadine must only be taken according to your doctor's instructions. If you are using an antacid, you should leave an interval of 2 to 3 hours between taking the two medicines.
For infections of the urinary tract and genitals, adults should take 4 capsules (250 mg) once daily.
For all other infections (see under Indications) adults, children and infants over 45 kg in weight should take 2 capsules of Binozyt (250 mg) daily for a period of 3 days
Mode and duration of administration
The capsules should be token at least one hour before meals or no earlier than 2 hours after meals. The film-coated tablets and capsules must be swallowed whole with sufficient fluid and not chewed.
Please take the dose prescribed by your doctor on 3 successive days, if possible at the same time of day. The duration of use will depend exclusively on your doctor's instructions. Do not stop taking your Binozyt treatment without consulting your doctor. If you do, your condition could be made worse.
If you forget to take your Binozyt, take the intended dose as soon as you remember. Then continue your treatment as normal.
Symptoms include nausea, vomiting, diarrhoea, and prostration. Treatment is supportive and symptomatic.
Binozyt is generally very well tolerated, but medicines can also have undesired effects. If the following list of possible side effects causes you concern, please remember:
- This list includes almost all observed side effects, even those which are extremely rare.
- Side effects do not occur in every patient.
Hypersensitivity reactions such as skin and mucous membrane reactions are rare, e.g. redness with or without itching, sensitivity to light (especially sunlight and UV rays), pains in the joints, swelling and nettle rash. As with other antibiotics, hypersensitivity symptoms can be severe, i.e. causing allergic - in some cases even fatal -Reactions (shortness of breath, vomiting, dizziness and hypotension).
In some cases the symptoms re-appear and require long-term monitoring or treatment.
Problems may occasionally occur in the form of loss of appetite, impaired digestion, loose stools, upper abdominal complains (pain, cramps), nausea, vomiting, diarrhoea (in rare cases involving considerable loss of fluid), constipation and flatulence.
Liver and bile ducts:
Cases of impaired liver function including heparins and jaundice have been reported.
Inflammation of the kidneys and acute renal failure have been reported.
In rare cases there were changes in the blood picture.
Palpitations, chest pains and irregular heart beat (as with other macrolides) have been reported.
Skin reactions rarely occur, sometimes involving the mucous membranes (erythema multiforme and Stevens-Johnson syndrome) and tissue necrosis.
Other side effects:
Fungal infections of the vagina rarely occur. Dizziness, vertigo, cramps, headaches, drowsiness and weakness and impaired sensation have been observed.
As with other macrolide antibiotics, treatment with Binozyt in a few cases resulted in impaired hearing (reduced acuity, deafness, tinnitus). Many of these reports were associated with long-term use of high doses in clinical studies. There have been rare reports of altered sense of taste.
Expiry date and storage
Please note the expiry date.
The expiry date for this medicine is printed on the pack.
Do not use this medicine after the expiry date shown.
Store in the original package below 30° C.
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