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Brand Names: Atarax, Alamon, Aterax, Durrax, Tran-Q, Orgatrax, Quiess, Vistaril Parenteral, and Tranquizine
Generic Name: Hydroxyzine Hydrochloride
Hydroxyzine dihydrochloride film-coated tablets - syrup
Tranquillizer with antihistaminic action
MAIN PHARMACOLOGICAL ACTIVITIES
Tranquillizing, antihistaminic, antisecretory, antiemetic, antispasmodic, local anesthetic (conduction, surface or infiltration anesthesia), narcotic and barbiturate-potentiating activities.
INDICATIONS - DOSAGE
Psychic disorders : nervous tension, anxiety, anguish; neurotic conditions, exogenous depression, non-psychotic character disturbances (irritability, aggressivity); non-psychotic agitation, nervous sleeplessness, acute and chronic ethylism.
Internal medicine : nervous stress, anxiety and neurovegetative disorders in cardiovascular affections (hypertension, arteriosclerosis, arrhythmia, stenocardia, nervous and circulatory asthenia), respiratory affections (nervous cough, chronic bronchitis, bronchospasmsl, gastrointestinal disorders (nausea and vomiting, gastric hypermotility and hypersecretion, gastric and duodenal ulcers, chronic colitis), and in pediatrics (tics, enuresis).
Psychic and neurovegetative disorders in connection with puberty, menstruation and menopause.
Hay fever, vasomotor rhinitis, allergic asthma, digestive, skin and mucous membrane allergies (urticaria, angioneurotic edema, etc.).
Dermatology : pruriginous affections.
- Aged people, adults and children above 10 years : on an average, 50 to 100 mg daily in divided doses, i.e. 2 to 4 tablets of 25 mg, 2 to 3 tablespoonfuls of syrup.
- Children from 6 to 10 years : on an average, 30 to 60 mg daily in divided doses, i.e. 3 to 6 tablets of 10 mg, 3 to 6 teaspoonfuls of syrup.
- Children from l to 5 years : on an average, 20 to 30 mg daily in divided doses, i.e. 2 to 3 teaspoonfuls of syrup.
- Children from 6 months to 1 year : on an average,10 to 15 mg daily in divided doses, i.e. 2 to 3 half-teaspoonfuls of syrup.
It should be pointed out that the dosage is strictly individual and-must, if required, be adapted according to the therapeutical effect obtained.
Preparation for dental surgery or diagnostic interventions
- Adults and children above 10 years : 2 tablets of 25 mg each in a single intake, 30 to 45 minutes before the intervention.
Children under 10 years : in the form of 10 mg-tablets or, preferably in the form of syrup : about 1 mg/kg in a single intake 30 minutes before the intervention.
Sleep-inducing premedication : at bed-time the day before a surgical operation (ATARAX alone or associated with a barbiturate).
- Adults and children above 10 years : 2 to 4 tablets of 25 mg in a single intake.
Children under 10 years : a single intake of 1 mg/kg in the form of syrup or 10 mg tablets.
For conditions calling for emergency treatment there exists a form for injection of the product. It is advisable to switch to oral administration as soon as possible.
SUPPLIES AND FORMULAE
100,500, 5000 film-coated tablets each scored at 10 mg : Hydroxyzine 2 HCI10 mg.—Excip. q.s. by one f.c. tabl.
4, 10, 25, 100, 250, 500, 5000 film-coated tablets each scored at 25 mg :
Hydroxyzine 2 HCI 25 mg. — Excip. q.s. by one f.c. tabl.
30, 60, 200, 1000 ml of syrup scored at 2% : Hydroxyzine 2 HCI 10 mg.— Excip. : Ethyl alcohol —Hazelnut flavour — Menthol — Sodium benzoate — Sugar —Water q.s. for 5 ml.
Keep at room temperature 115 to 25 °C).
OTHER FORM OF SUPPLY
Solution for injection : 6 and 25 ampoules of 2 ml each scored at 100 mg.
In case of complaint, mention the batch control number indicated on the packing.
Why Atarax this drug prescribed?
Atarax is an antihistamine used to relieve the symptoms of common anxiety and tension and, in combination with other medications, to treat anxiety that results from physical illness. It also relieves itching from allergic reactions and can be used as a sedative before and after general anesthesia. Antihistamines work by decreasing the effects of histamine, a chemical the body releases that narrows air passages in the lungs and contributes to inflammation. Antihistamines reduce itching and swelling and dry up secretions from the nose, eyes, and throat.
Most important fact about this drug
Atarax is not intended for long-term use (more than 4 months). Your doctor should re-evaluate the prescription periodically.
How should you take this medication?
Take this medication exactly as prescribed by your doctor.
If you miss a dose
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
Store tablets and syrup away from heat, light, and moisture. Keep the syrup from freezing.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Atarax.
Drowsiness, the most common side effect of Atarax, is usually temporary and may disappear in a few days or when dosage is reduced. Other side effects include dry mouth, twitches, tremors, and convulsions. The last two usually occur with higher than recommended doses of Atarax.
Why should this drug not be prescribed?
Atarax should not be taken in early pregnancy or if you are sensitive to or have ever had an allergic reaction to it. Make sure your doctor is aware of any drug reactions you have experienced.
Special warnings about this medication
Atarax increases the effects of drugs that depress the activity of the central nervous system. If you are taking narcotics, non-narcotic analgesics, or barbiturates in combination with Atarax, their dosage should be reduced.
This medication can cause drowsiness. Driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended until you know how you react to Atarax.
Possible food and drug interactions when taking this medication
Atarax may increase the effects of alcohol. Avoid alcohol while taking this medication.
If Atarax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Atarax with the following:
Barbiturates such as Seconal and Phenobarbital
Narcotics such as Demerol and Percocet
Non-narcotic analgesics such as Motrin and Tylenol
Special informationif you are pregnant or breastfeeding
Although the effects of Atarax during pregnancy have not been adequately studied in humans, birth defects have appeared in animal studies with this medication. You should not take Atarax in early pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Atarax may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Any medication taken in excess can have serious consequences. If you suspect an overdose of Atarax, seek medical attention immediately.
The most common symptom of Atarax overdose is excessive calm; your blood pressure may drop, although it is not likely.
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